It is a different life, a different feeling... those who live with earth under their feet, even those who travel a little, can't understand it. When you choose life on a space ship, it is a leap of faith. Not only to freedom, but to a risky existence with few guarantees, the emptiness of space only inches away from you, for your whole life. Can you imagine that?
(Crewman Hobart, trying to pick up a passanger.)
Herein lies a smattering of plot hooks for the Firefly setting, gathered from the dirty corners of forums and minds, in the hope that they would stop haunting them. If anyone wants to game in this setting, then plot hooks will they need.
A campaign of this kind doesn't have a stable home base. The intrepid crew truly lives on their spaceship, roaming through their part of universe, braving adventures, and trying to get paid (and not shot... too often). Theirs may not be the most epic of adventures, but they do have their own charm.
Note: many of the plot hooks listed below can be adapted for a naval campaign or adventure.